The star has handed over the entirety of his £25,000 honor cash to the trust for venues, which works to protect the UK's independent live music spots.
Fender was presented with the award on mid-October as his new release his work was declared the top album of the past year.
Fender has opted to give the cash to the MVT, in recognition of the vital role grassroots venues fulfilled in his beginning days.
"I personally would not have achieved this success if it weren't for all the performances I did around the North East, and beyond, when I was starting out," said Sam Fender. "These venues are iconic, but they are struggling."
From early 2023 onward, more than 150 of these venues have ceased operations – approximately one-sixth of the total UK scene.
In the last year, well-known musicians including Pulp, Coldplay, Katy Perry and Ed Sheeran have all aided the MVT in its initiatives to keep the scene afloat, by applying a modest fee to their ticket costs, which supports independent venues.
Fender also joined in, collecting in excess of £100,000 on his recent tour to help 38 grassroots venues across England, Scotland, and Wales.
The money supported locations that were dealing with imminent closure due to challenges stemming from flooding, fires and personal losses, as well as regulatory hurdles, court cases and sound issues.
Some locations obtained funding support in modernizing infrastructure and technical equipment that helped musicians and audiences.
"The notion that revenue from performances in major spaces supports the independent spots, where it kicks off for artists like me, is just logical," Fender has stated.
Fender is far from the only musician to contribute his award prize money to worthy causes.
In Pulp received the prize in 1996 for their album Different Class, vocalist Jarvis Cocker declared that the act would donate their cash to the charity War Child.
In 2002, artist Ms Dynamite split her award across a few charities, like the children's charity and a charity for Sickle Cell.
"And I donated a grand to Highgate Newtown, to their gymnastics class, because I trained in gymnastics when I was a child and they required new equipment," the artist told the media.
In recent years, Ezra Collective contributed their prize money to the local youth club that nurtured their group, alongside other independent music bodies.
And the 1994 recipients the group gave their winnings to a MS organization after a friend was found to have the condition.
"Winning was ample," remarked vocalist Heather Small. "The cash was the extra but we could do without the extra, because we had the main prize. So our winning touched the lives of others."
Recently, the trust shared it had protected two small stages in that region, by transferring them to public stewardship.
The first in Southampton and the second in Bristol were purchased under the Own Our Venues scheme, which is backed by Arts Council England and music fans who acquire "ownership units" in the venues.